In situ synthesis of AgI on the nanosilica surface for potential application as a cloud seeding material.

A series of nanosilica/AgI composites was synthesized by in situ reactions between silver nitrate and ammonium iodide deposited on the nanosilica surface using the gas-phase solvate-stimulated mechanosorption modification (GSSMSM) under both dry and wet conditions. The characterization of the synthesized materials was performed by X-ray diffraction (XRD), SEM/EDX (Scanning Electron Microscopy-Energy Dispersive X-ray), thermogravimetric (TGA) and gas sorption methods. As a result of the mechanosorption modification of nanosilica, the bulk density of the samples synthesized in the dry and wet medium increases from 45 g/l for initial nanosilica to 249 g/l and 296 g/l for the modified samples, respectively.

Nanostructure and thermal characteristics of silica/human serum albumin systems based on a modified nanosilica entero-vulnerosorbent.

Entero-vulnerosorbents based on geometrically modified (GM) (mechanical treatment at different times, = 1, 4, and 7 h) fumed nanosilica A300 (NS) and protein molecules (human serum albumin/GM-nanosilica systems) were characterized with a focus on their surface, morphology, topography, and thermal properties. Microscopic, spectroscopic, and analytical techniques, including atomic force microscopy (AFM), optical profilometry (OP), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS), and elemental analysis (CHN), were used. The differentiation in the surface morphology, micro-nanoroughness, surface chemistry, thermal properties of the silica support, and protein/nanosilica systems were found.

Chitosan-Silica Composites for Adsorption Application in the Treatment of Water and Wastewater from Anionic Dyes.

A series of new types of composites (biopolymer-silica materials) are proposed as selective and effective adsorbents. A new procedure for the synthesis of chitosan-nanosilica composites (ChNS) and chitosan-silica gel composites (ChSG) using geometrical modification of silica and mechanosorption of chitosan is applied. The highest adsorption efficiency was achieved at pH = 2, hence the desirability of modifications aimed at stabilizing chitosan in such conditions.

Effect of geometric modification of fumed nanoscale silica for medical applications on adsorption of human serum albumin: Physicochemical and surface properties.

The influence of the geometric modification (GM) of fumed nanoscale silica A300 (NS) on the adsorption capacity of human serum albumin (HSA) as well as the physicochemical and textural properties of the protein/nanosilica system was analyzed. An effective medical enterosorbent based on fumed nanosilica was designed and produced in the Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine. To design an effective nanomaterial for biomedical applications as a wound-healing material, the adsorption, physicochemical and surface properties of the initial nanosilica (NS), nanosilica after geometric modification (GM-nanosilica), and HSA/nanosilica biocomposites were characterized.

Synthesis and Comparative Study of Anti-Adenoviral Activity of 6-Azacytidine and Its Analogues.

This paper presents the results of synthesis and study of cytotoxicity and the anti-adenoviral activity of new N4-derivatives of 6-azacytidine and its α-L-glycopyranosyl analogues obtained by the simplified one-pot version of the silyl condensation method. The resulting acylated 4-methylmercapto-1,2,4-triazin-3(2Н)-one glycosides then underwent the amination and/or ammonolysis to provide 6-azacytidine glycoside analogues (2-6, 12, 15, 17) and compounds with modifications at both base and sugar fragments (11, 15). The evaluation of cytotoxicity and antiviral activity of new compounds against AdV5 showed high selectivity indexes for N4-methyl-6-azacytidine (2) and N,O-tetraacetyl-6-azacytidine (8).