Differential Expression Analyses on Human Aortic Tissue Reveal Novel Genes and Pathways Associated With Abdominal Aortic Aneurysm Onset and Progression.

Background: Abdominal aortic aneurysms (AAAs) are focal dilatations of the abdominal aorta that expand progressively, increasing their risk of rupture. Rupture of an AAA is associated with high mortality rates, but the mechanisms underlying the initiation, expansion, and rupture of AAAs are not yet fully understood. We aimed to characterize the pathophysiology of AAAs and identify new genes associated with AAA initiation and progression.

Hydrops Gallbladder Caused by Cystic Duct Fibrosis Leading to Mirizzi Syndrome: A Case Report.

Mirizzi syndrome (MS) is a rare complication of cholelithiasis, resulting from the extrinsic compression of the common hepatic duct or common bile duct by impacted gallstones in the cystic duct or Hartmann's pouch. MS is most commonly observed in the elderly with a long-standing history of gallstones. We present the case of MS type I diagnosed following magnetic resonance cholangiopancreatography (MRCP).

Why do some Mexicans with psychosis risk symptoms seek mental health care and others do not?

Help-seeking barriers differ according to the sociocultural context and country-specific mental healthcare system. More research is needed in low-middle-income countries, where early psychosis programs are still scarce, and the mental health care gap is wide. This study aims to explore predisposing, enabling, and need factors associated with mental health service utilization in 481 Mexicans self-reporting psychosis risk symptoms, as well as differences between those who were currently mental health service users (MHSU) and those who were not (non-MHSU).

Single center assessment of the role of Oakland score among patients admitted for acute lower gastrointestinal bleeding.

Background/objectives: The Oakland score was developed to predict safe discharge in patients who present to the emergency department with lower gastrointestinal bleeding (LGIB). In this study, we retrospectively evaluated if this score can be implemented to assess safe discharge (score ≤ 10) at WellStar Atlanta Medical Center (WAMC).

Methods: A retrospective cohort study of 108 patients admitted at WAMC from January 1, 2020 to December 30, 2021 was performed.

Is calcium deficiency the real cause of bitter pit? A review.

Bitter pit is a disorder affecting the appearance of apples. Susceptibility is genetically controlled by both the cultivar and rootstock, with both environmental and horticultural factors affecting its severity and proportional incidence. Symptoms appear more frequently at the calyx end of the fruit and consist of circular necrotic spots, which take on a "corky" appearance visible through the peel.