Publications by authors named "L M Nardelli"
We describe the epidemiology of cancer after kidney transplantation (KTx), investigating its risk factors and impact on therapeutic management and survival in KTx recipients (KTRs). The association between modification of immunosuppressive (IS) therapy after cancer and survival outcomes was analyzed. We collected data from 930 KTRs followed for 7 [1-19] years.
View Article and Find Full Text PDFIntroduction And Aim: Hepatitis C virus infection and chronic kidney disease are major public health issues all over the world. It has been suggested a role of HCV as a risk factor for the development and progression of chronic kidney disease (defined by reduced glomerular filtration rate and/or detectable proteinuria) in the general population but conflicting findings have been given.
Material And Methods: A systematic review of the published medical literature was conducted to assess whether positive HCV serologic status is associated with greater rate of proteinuria in the adult general population.
Patients affected by chronic kidney disease (CKD) are generally considered to be frailer than those with preserved renal function. We cross-sectionally evaluated the associations between frailty, malnutrition-inflammation syndrome and circulating inflammatory cytokines in 115 older individuals with advanced CKD. As for frailty definition, we adopted Fried's frailty phenotype (FP), while malnutrition-inflammation syndrome was assessed using the Malnutrition-Inflammation Score (MIS) and circulating inflammatory cytokines (IL-6; TNFα; MCP-1).
View Article and Find Full Text PDFArticle Synopsis
- Diabetes mellitus (DM) has significant impacts on kidney and liver functions, leading to conditions like diabetic kidney disease (DKD) and metabolic dysfunction-associated steatotic liver disease (MASLD).
- Management strategies for DKD include lifestyle changes and medications focusing on blood pressure and blood sugar control, while lifestyle modifications like weight loss and a Mediterranean diet are essential for MASLD.
- There's a critical need for screening and tailored care for patients with DM and liver issues, especially in unique populations such as those on hemodialysis or kidney transplant recipients, highlighting the importance of a multidisciplinary approach.
Background: Peritonitis is a common and severe complication of peritoneal dialysis (PD). For comparative analysis standardized definitions as well as measurements and outcomes are crucial. However, most PD-related peritonitis studies have been using heterogenous definitions and variable methods to measure outcomes.
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