Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance.

Aim. The evaluation of the clinical relevance of disseminated tumor cells (DTCs) in bone marrow (BM) of patients with gastric cancer (GC) and their association with primary tumor hypoxia. Patients and Methods.

[Hygienic assessment of biological reservoir pollution in Eastern Siberia and the North].

The paper presents the characteristics of microbial communities in the water reservoirs of Eastern Siberia and North and their changes depending on the anthropogenic pollution and analyzes antibiotic resistance in microorganisms. The water contamination with pathogenic viruses was revealed in relation to the man-made load, which may be a criterion for assessing the epidemiological situation on the territories.

[Problems of epidemic safety of drinking water use by the population of Russia].

Quantitative relationships were studied between the indicators (common coliform bacteria (CCP), glucose-positive bacteria (GPB), thermoduric bacteria (TDB), coliform bacteria, enterococci, clostridia, coliphages) and the opportunistic (Pseudomonas aeruginosa, Proteus, Klebsiella) and pathogenetic (Salmonella and intestinal viruses) microorganisms at the stages of effluent purification and decontamination, in processes of self-purification in the water reservoirs and of water preparation at water-supplying stations, as well as in the association with the incidence of acute intestinal infections of bacterial and viral genesis in different climatic zones of the country. Salmonella and the opportunistic bacteria of the Enterobacteriaceae family and Pseudomonas aeruginosa were found to be highly resistant to detoxifying agents and environmental factors, adaptable, able to reproduce in pure water, to long survive in underground waters, and to accumulate when water is desalinated at the erections. The cases of intestinal infections were found in the population using the portable water of the standard quality in terms of E.

[Indications of pathogenic viruses in water of Lake Baikal and its tributaries].

The waters of 25 large rivers falling into the Baikal Lake, their mouth water areas and open Baikal Lake areas to a depth of 500 m were for the first time in the practice of researches on the Baikal Lake were investigated for markers of hepatitis A virus and rotaviruses. The investigations showed an insignificant contamination of surface waters with pathogenic viruses. The antigens of all studied viruses and high values of bacteria from the Escherichia coli group were recorded in the areas exposed to chronic man-made pollution.