Publications by authors named "L M Lapina"

Article Synopsis
  • CRUSE® is an app designed for people with chronic spontaneous urticaria (CSU) to track their symptoms using visual analogue scales (VASs), aiming to assess the app's effectiveness in measuring disease activity.
  • A study analyzed three VASs related to CSU impact on daily life, including one specifically for the severity of urticaria, one for productivity, and a general health measure (EQ-5D), using data from nearly 6,000 patients over many days.
  • The results showed that the CRUSE® app's VASs demonstrate strong validity and reliability, with the "VAS urticaria" being most effective in capturing symptom changes, while the minimal important difference (MID) values indicated meaningful changes
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Article Synopsis
  • * The study involved 140 CSU patients primarily comprising females with a mean age of 41.3, with many experiencing associated symptoms and identifiable triggers; 85.7% were treated with second-generation antihistamines.
  • * Results indicated severe disease in a substantial portion of patients, with poor control over symptoms and a notable impact on mental health, stressing the need for improved patient care and further research on treatment efficacy.
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Background: Chronic spontaneous urticaria (CSU) is unpredictable and can severely impair patients' quality of life. Patients with CSU need a convenient, user-friendly platform to complete patient-reported outcome measures (PROMs) on their mobile devices. CRUSE , the Chronic Urticaria Self Evaluation app, aims to address this unmet need.

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The article substantiates the actuality of legal normative support of maintenance of quality of medical activities. The analysis is presented concerning actual normative legal base in the Russian Federation regulating control of volumes, terms, quality and conditions of medical care provision. The evaluation is given concerning actual executive orders of Minzdrav of Russia regulating quality of medical care.

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Inelastic nuclear interaction probability of 400 GeV/c protons interacting with bent silicon crystals was investigated, in particular for both types of crystals installed at the CERN Large Hadron Collider for beam collimation purposes. In comparison to amorphous scattering interaction, in planar channeling this probability is for the quasi-mosaic type (planes (111)), and for the strip type (planes (110)). Moreover, the absolute inelastic nuclear interaction probability in the axial channeling orientation, along the axis, was estimated for the first time, finding a value of for a crystal 2 mm long along the beam direction, with a bending angle of 55 rad.

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