Humoral antitumor cytotoxins were found in most of assayed sera from melanoma patients. The patients' sera can cross-react in cytotoxic reactions in vitro with allogenic cell-targets of melanoma. The sera of healthy donors prove to be cytotoxic for melanoma cell-targets in vitro, the degree of their cytotoxicity being similar to that of autologous sera.
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October 1975
Radiation of a powerful neodymium-doped glass pulsed laser, Pulsar-1000 type, has been used for therapy of 235 patients with a total of 257 precancerous lesions and benign tumours, 76 basal and squamous cell carcinomas, 13 melanoblastomas and 59 metastatic melanoblastomas in the skin. Energy density used in the treatment of precancerous lesions and benign tumours was 200-450 J/cm2, in basal and squamous cell carcinomas 400-500 J/cm2, in melanoblastomas and their skin metastases 800-1 000 J/cm2. The results have been satisfactory.
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