Partially Sulfated Pillar[5]Arenes: Synthesis and Molecular Recognition Properties.

We report the synthesis and characterization of sulfated pillar[5]arene hosts (P5S-P5S) that differ in the number of sulfate substituents. All five P5S hosts display high solubility in water (73-131 mM) and do not undergo significant self-association according to H NMR dilution experiments. The x-ray crystal structures of P5S, P5S ⋅ MeHDA, P5S ⋅ MeHDA, and P5S ⋅ MeHDA reveal one intracavity molecule of MeHDA and several external molecules of MeHDA which form a network of close methonium ⋅ ⋅ ⋅ sulfate interactions.

Insoluble Acyclic Cucurbit[n]uril-Type Receptors Capture Iodine from the Vapor Phase.

Nuclear energy makes large contributions toward meeting global energy needs, but societal concerns remain high given the impacts of the intended release of radioactive materials including I and I. In this paper we explore the use of a homologous series of acyclic CB[n] type hosts (H1-H4) as adsorbents of iodine from the vapor phase. We find that H2-H4, but not H1 - perform well in this application with uptake capacities of 2.

NASC 2023: Showcasing Diversity in North American Supramolecular Chemistry.

Diversity in supramolecular chemistry can showcase itself in many ways. This includes the diversity of thought and topics covered in research (from fundamental science to applications in biology and materials), as well as the diversity of people (e.g.

The Missing Trial Variable: A Case Report on Dietary Modification in a Patient with Durable Complete Remission After an Immunotherapy Clinical Trial for Metastatic Bladder Cancer.

A patient with metastatic bladder cancer has had an ongoing 9-year complete remission on a clinical trial of immunotherapy with nivolumab and ipimumab, but he also was following an intensive dietary and nutritional supplement regimen. Whether this combination or the immunotherapy alone brought about his good outcome is unknown but could be clarified in future trials by improved data collection about dietary and supplement choices.