Publications by authors named "L M Geller"
Article Synopsis
- The study investigates how local impedance (LI) changes during ablation procedures can predict the effectiveness of creating lesions in heart tissue.
- Researchers analyzed data from over 600 ablation applications, finding that successful applications had a significant and sustained drop in LI, while unsuccessful ones only showed a minor decrease.
- The results suggest that monitoring LI drop, especially within the first 4 seconds of treatment, can be a useful indicator for the likelihood of effective lesion formation in cardiac ablation.
Ablation of Supraventricular Arrhythmias With as Low as Reasonably Achievable X-Ray exposure (AALARA): Results of Prospective, Observational, Multicenter, Multinational, Open-Label Registry Study on Real World Data Using Routine Ensite 3D Mapping During SVT Ablation.
Pacing Clin Electrophysiol
November 2024
Introduction: The reduction of fluoroscopic exposure during catheter ablation of supraventricular arrhythmias is widely adopted by experienced electrophysiology physicians with a relatively short learning curve and is becoming the standard of care in many parts of the world. While observational studies in the United States and some parts of Western Europe have evaluated the minimal fluoroscopic approach, there are scarce real-world data for this technique and the generalizability of outcomes in other economic regions.
Method: The AALARA study is a prospective, observational, multicenter, and multinational open-label study.
Article Synopsis
- The study aimed to validate the SEMMELWEIS-CRT score for predicting 1-year all-cause mortality in patients receiving Cardiac Resynchronization Therapy (CRT) using a large European dataset.
- The tool showed strong predictive ability, with an area under the receiver operating characteristic curve (AUC) of 0.729, and outperformed traditional risk scores while correlating higher predicted mortality with increased hospitalization risks.
- The findings confirm the SEMMELWEIS-CRT score's effectiveness and potential clinical use as a reliable tool for risk stratification in CRT patients.
Article Synopsis
- The study investigates the effectiveness of high-power short-duration (90 W/4 s) radiofrequency ablation for pulmonary vein isolation (PVI) in patients with atrial fibrillation, particularly looking at gaps in ablation lines that can lead to recurrences.
- Using data from 20 patients and analyzing 1,357 ablation points, the researchers identified key factors affecting the occurrence of these gaps, including interlesion distance (ILD) and generator impedance.
- The findings suggest that smaller ILDs (3.5 mm anteriorly and 4 mm posteriorly) improve the durability of PVI, indicating that adjustments in ablation techniques might be necessary compared to traditional approaches.
Article Synopsis
- This study examines the relationship between body mass index (BMI) and all-cause mortality in patients eligible for cardiac resynchronization therapy (CRT), focusing on the "obesity paradox," where obesity may sometimes correlate with better health outcomes.
- A total of 1,585 patients were categorized by BMI into normal weight, overweight, and obese groups, with the findings showing that obese patients had a lower mortality rate compared to normal-weight patients over a mean follow-up of 5.1 years.
- The research indicates that factors like diabetes and hypertension are more prevalent in those with higher BMI, but despite this, the lower mortality in obese patients suggests an intriguing relationship that warrants further investigation.