Publications by authors named "L M Estela Villa"
Cefiderocol (FDC), a siderophore-cephalosporin conjugate, is the newest option for treating infection with carbapenem-resistant gram-negative bacteria. We identified a novel mechanism contributing to decreased FDC susceptibility in Klebsiella pneumoniae clinical isolates. The mechanism involves 2 coresident plasmids: pKpQIL, carrying variants of bla carbapenemase gene, and pKPN, carrying the ferric citrate transport (FEC) system.
View Article and Find Full Text PDFStaphylococcus aureus is the main etiologic agent of contagious dairy cow mastitis, while non-aureus staphylococci and mammaliicocci (NASM) are the bacteria most frequently isolated from milk. Beyond their impact on animal health, NASM can harbor antimicrobial resistance (AMR) genes with potential for bidirectional transfer with S. aureus, and methicillin-resistant (MR) staphylococci (MRS) can raise significant One Health concerns.
View Article and Find Full Text PDFArticle Synopsis
- The review aimed to evaluate the effects of pulse modulation technology on laser lithotripsy and prostate enucleation in endourology, focusing on efficiency, safety, and tissue interaction.
- A systematic search of studies from the last 20 years identified 29 articles that examined these technologies, with preclinical studies showing promise in stone fragmentation but mixed results in clinical settings.
- While pulse modulation can improve operational efficiency and reduce thermal safety risks, its benefits for prostate surgery outcomes remain inconsistent, yielding comparable rates to standard modalities in terms of stone-free status and complications.
Oral human papillomavirus (HPV) is associated with oropharyngeal cancer (OPC). Although OPC incidence is increasing globally, knowledge of oral HPV infection rates is limited. Here we carried out an observational epidemiological analysis of oral HPV incidence in 3,137 men enrolled from the United States, Mexico and Brazil between 2005 and 2009.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses a case of bacteremia caused by non-O1/non-O139 strains (NOVC) of a Gram-negative bacterium, which can occasionally lead to severe infections in immunocompromised individuals.
- It focuses on a 71-year-old patient with advanced lung cancer who experienced fever, confusion, and asthenia due to NOVC bacteremia, confirmed through blood cultures.
- The patient responded well to treatment with antibiotics (ceftriaxone and ciprofloxacin), highlighting the need for quick diagnosis and targeted therapy in similar cases.