Publications by authors named "L M East"
Article Synopsis
- Eteplirsen, golodirsen, and casimersen are drugs approved for treating Duchenne muscular dystrophy (DMD) that target specific genetic mutations associated with the disease through a mechanism called exon skipping.
- In studies, these drugs showed similar metabolism and pharmacokinetic properties across various animal models, with consistent plasma exposure and low plasma protein binding.
- The research suggests that these PMOs share key characteristics that could support the development of a broader PMO drug class, potentially leading to new treatments for genetic conditions like DMD.
Aim: To explore the demographics, employment characteristics, job satisfaction and career intentions of the Australian nursing and midwifery academic workforce.
Background: The academic workforce is crucial in preparing the next generation of nurses and midwives. Thus, understanding current satisfaction, challenges, opportunities and intentions is important for recruitment and succession planning.
Aim: This study aimed to explore what changes rural placement had on the perceptions of nursing students and the impact of placement frequency and duration on student considerations for rural practice.
Background: A strong rural healthcare workforce is a global concern and has led countries to look for creative ways to address this challenge. One approach is to train more health professionals, however, nursing students who grew up or lived in metropolitan or urbanised areas are suggested to be less inclined to pursue a rural career.
Background: Extreme obesity is a global health issue impacting health and related health outcomes. Although extreme obesity is prevalent across all geographical settings, the condition is more common in geographically isolated locations. The success of mainstream weight loss strategies such as surgery, exercise, and dietary information within these communities remains unknown, and it is unclear if isolation facilitates or hinders treatment for weight management.
View Article and Find Full Text PDFBackground: Since its emergence, the COVID-19 pandemic has compromised the food security both directly by impacting food supply chain and indirectly by overwhelming the individual health and/or personal financial situation. The overarching aim of the current study is to assess aspects of the food security crisis that have arisen due to COVID-19 and to identify which, if any, food security dimensions were specifically compromised.
Methods: Primary research articles were initially identified through four online databases (Scopus, PubMed, Google Scholar, and Web of Science), with the references of each paper then also reviewed for additional article.