Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer.

Background: Despite extensive analysis, the dynamic changes in prostate epithelial cell states during tissue homeostasis as well as tumor initiation and progression have been poorly characterized. However, recent advances in single-cell RNA-sequencing (scRNA-seq) technology have greatly facilitated studies of cell states and plasticity in tissue maintenance and cancer, including in the prostate.

Methods: We have performed meta-analyses of new and previously published scRNA-seq datasets for mouse and human prostate tissues to identify and compare cell populations across datasets in a uniform manner.

The genome sequence of an ichneumonid wasp, (Muller, 1776).

We present a genome assembly from an individual male ichneumonid wasp, (Arthropoda; Insecta; Hymenoptera; Ichneumonidae). The genome sequence has a total length of 270.30 megabases.

The genome sequence of the Broad-barred Knot-horn, (Hübner, 1813).

We present a genome assembly from one female (the Broad-barred Knot-horn; Arthropoda; Insecta; Lepidoptera; Pyralidae). The genome sequence is 598.4 megabases in span.

The genome sequence of the sycamore periphyllus aphid, (Walker, 1848).

We present a genome assembly from an individual female (the sycamore periphyllus aphid; Arthropoda; Insecta; Hemiptera; Aphididae). The genome sequence has a total length of 405.30 megabases.