A map of the rubisco biochemical landscape.

Rubisco is the primary CO-fixing enzyme of the biosphere, yet it has slow kinetics. The roles of evolution and chemical mechanism in constraining its biochemical function remain debated. Engineering efforts aimed at adjusting the biochemical parameters of rubisco have largely failed, although recent results indicate that the functional potential of rubisco has a wider scope than previously known.

Antimicrobial prescribing quality in Australian emergency departments: an analysis of the Hospital NAPS data set.

Objective: To analyze antimicrobial prescribing practices in Australian emergency departments (ED), identifying prescribing areas requiring improvement. This aims to inform antimicrobial stewardship (AMS) strategies to enhance antimicrobial prescribing quality.

Design: Retrospective analysis of the Hospital National Antimicrobial Prescribing Survey (NAPS) data set.

VHA Support for Home Health Agency Staff and Patients During Natural Disasters.

Background: Home health agencies (HHAs) provide vital community-based services for older adults. Under-resourced HHAs that are disconnected from broader community emergency planning efforts may struggle to maintain services during emergencies. As climate-related disasters become more prevalent, HHA services are increasingly at risk, and policymakers have focused on the services they provide to older adults.

The effectiveness of harvest for limiting wildlife disease: Insights from 20 years of chronic wasting disease in Wyoming.

Effective, practical options for managing disease in wildlife populations are limited, especially after diseases become established. Removal strategies (e.g.