Publications by authors named "L Lustig"
Experimental autoimmune orchitis (EAO) is a well-established rodent model of organ-specific autoimmunity associated with infertility in which the testis immunohistopathology has been extensively studied. In contrast, analysis of testis biopsies from infertile patients associated with inflammation has been more limited. In this work, testicular biopsies from patients with idiopathic non-obstructive azoospermia diagnosed with hypospermatogenesis (HypoSp) [mild: = 9, and severe: = 11], with obstructive azoospermia and complete Sp (spermatogenesis) (control group, C, = 9), and from Sertoli cell-only syndrome (SCOS, = 9) were analyzed for the presence of immune cells, spermatogonia and Sertoli cell (SCs) alterations, and reproductive hormones levels.
View Article and Find Full Text PDFObjective: To analyze the effect of visual abstracts versus automated tweets on social media participation in Otology & Neurotology .
Patients: N/A.
Interventions: Introduction of visual abstracts developed by the social media editorial team to established automated tweets created by the dlvr.
Varicocele and testicular cord torsion: immune testicular microenvironment imbalance.
Front Cell Dev Biol
November 2023
The main functions of the testis, steroidogenesis and spermatogenesis, depend on the endocrine axis and systemic and local tolerance mechanisms. Infectious or non-infectious diseases may disturb testicular immune regulation causing infertility. Literature has illustrated that bacterial and viral infections lead to autoimmune infertility: either sperm antibodies or autoimmune epidydimo-orchitis.
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- The study aimed to assess the 2-year outcomes of using lidocaine/epinephrine iontophoresis and an automated tube delivery system for pediatric tympanostomy in an office setting.
- The research involved 269 children treated in-office and 68 children in the operating room, following patients for tube retention and complications over 2 years.
- Results showed comparable tube retention rates and complication levels between in-office and traditional operating room procedures, indicating that the in-office method is a viable alternative.
Experimental autoimmune orchitis (EAO) is a chronic inflammatory disorder that causes progressive spermatogenic impairment. EAO is characterized by high intratesticular levels of nitric oxide (NO) and tumor necrosis factor alpha (TNFα) causing germ cell apoptosis and Sertoli cell dysfunction. However, the impact of this inflammatory milieu on the spermatogenic wave is unknown.
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