Publications by authors named "L Losco"
: Lymphedema is a progressive, chronic condition. Traumatic damage to the lymphatics, removal of lymph nodes, and/or radiation are the major causes of fibrosis and a subsequent pathological cascade. Macrophages play a crucial role in wound healing, with M1 macrophages known for their pro-inflammatory effects and M2 macrophages recognized for their anti-inflammatory effects, including improved angiogenesis, lymph angiogenesis, and tissue healing.
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- - The study explores how leg dominance affects the choice of perforator flap donor sites for reconstruction surgeries using advanced imaging techniques to enhance preoperative planning.
- - In a sample of 40 patients, most (87.5%) were right-leg dominant, showcasing that the dominant leg typically has larger and more numerous perforators for certain flap types compared to the nondominant leg.
- - Results suggest that surgeons may benefit from prioritizing the dominant leg as a donor site, as it has better vascular characteristics and muscle thickness for improving surgical outcomes, although no significant differences were found in the subcutaneous tissue thickness.
: Amelanotic/hypomelanotic melanomas (AHMs) account for 2-8% of all cutaneous melanomas. Due to their clinical appearance and the lack of specific dermoscopic indicators, AHMs are challenging to diagnose, particularly in thinner cutaneous lesions. The aim of our study was to evaluate the clinicopathological and dermoscopic features of thin AHMs.
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