Chemistry to cognition: Therapeutic potential of (m-CF-PhSe) targeting rats' striatum dopamine proteins in amphetamine dependence.

Amphetamine (AMPH) abuse represents a major global public health issue, highlighting the urgent need for effective therapeutic interventions to manage addiction caused by this psychostimulant. This study aimed to assess the potential of m-trifluoromethyl-diphenyldiselenide [(m-CF-PhSe)] in preventing the addictive effects induced by AMPH through targeting dopamine metabolism proteins. (m-CF-PhSe) is of interest due to its demonstrated efficacy in mitigating opioid abuse, establishing it as a promising candidate for addiction treatment research.

Kapok fibers modified with cationic surfactants: Structural insights and efficient removal of Cr(VI) and bisphenol A.

In this study, kapok fiber (KF) a hollow and hydrophobic fiber, was modified with cetyltrimethylammonium bromide (CTAB) or cetylpyridinium chloride (CPC), rendering adsorbed amount of ∼0.75 × 10 mol/g. Small-angle X-ray scattering (SAXS) measurements of dry KF/CTAB and KF/CPC evidenced a periodic distance of ∼2.

Coconut Oil Mitigates the Effects of Aging on the Mongolian Gerbil Prostate.

Background: Benign prostatic hyperplasia (BPH) is a disease linked to the hormonal imbalance that occurs during aging and over the last decades, complementary and alternative medicines have come on the scene as a treatment option for BPH, such as herbal medicines. Coconut oil has been shown to be capable of interfering in testosterone-induced BPH. However, until now there is no study of the effect of coconut oil during aging.

Chrysin modulates the BDNF/TrkB/AKT/Creb neuroplasticity signaling pathway: Acting in the improvement of cognitive flexibility and declarative, working and aversive memory deficits caused by hypothyroidism in C57BL/6 female mice.

Hypothyroidism is known to affect memory consolidation, and our prior research highlighted the potential of chrysin as a therapeutic agent to restore cognitive function. The present study aimed to investigate the action mechanism of chrysin on memory deficits in hypothyroid in C57BL/6 female mice. We assessed cognitive flexibility, declarative, working, and aversive memories while analyzing the BDNF/TrkB/AKT/Creb neuroplasticity signaling pathway and synaptic function in the hippocampus and prefrontal cortex.

The impact of neonicotinoid insecticides on amphibians: A comprehensive review and future research challenges.

Neonicotinoid insecticides (NNIs) are widely used in agriculture; however, their effects on anuran amphibians remain poorly explored. This global review critically examines the existing literature, with data obtained from Web of Science and Scopus databases. A total thirty-seven studies were published from 2004 to 2023.