Publications by authors named "L Longo"
Background: Genetic and epigenetic alterations are related to metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis.
Aim: To evaluate micro (mi)RNAs and lipophagy markers in an experimental model of metabolic dysfunction-associated steatohepatitis (MASH).
Methods: Adult male Sprague Dawley rats were randomized into two groups: Control group ( = 10) fed a standard diet; and intervention group ( = 10) fed a high-fat-choline-deficient diet for 16 weeks.
Article Synopsis
- Polyphosphate kinase 2 (PPK2) enzymes are key to transferring phosphate to nucleotides and are categorized into three classes, each with unique preferences.
- The study of PPK2's distribution among prokaryotes helps understand its evolutionary history and potential adaptations across various species.
- Observations revealed a significant preference for Class I enzymes in species with multiple PPK2 genes, alongside insights about gene duplication and possible functional versatility that challenge previous understandings of PPK2 evolution.
Introduction: Treatment with nonresorbable antibiotics is effective in diarrhea-predominant irritable bowel syndrome (IBS-D). Multimatrix (MMX) formulations ensure targeted drug delivery to the mid-distal small bowel and colon-traditionally considered the origin of IBS symptoms. To assess the efficacy of rifamycin SV-MMX for the treatment of IBS-D.
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- * Cardiovascular events are the most common life-threatening complications, including oculocardiac reflex and iatrogenic vascular air embolism, which can lead to severe consequences like respiratory distress.
- * The review discusses potential complications, focusing on their causes, risk factors, symptoms, and management strategies, with particular attention to rare but serious infections like necrotizing fasciitis.
Background: Disturbances in the gut microbiota may act as mechanisms influencing the interplay between dietary factors and metabolic disorders. Studies have demonstrated that these alterations are associated with the diagnosis of polycystic ovary syndrome (PCOS). Within this context, we aimed to investigate associations between gut microbiota, gut-derived metabolites (short-chain fatty acids [SCFAs] and indole-3-propionic acid [IPA]), and dietary intake in women with PCOS.
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