Publications by authors named "L Lo Giudice"
is a self-pollinating species belonging to the Poaceae family characterized by a resistance to drought higher than that of corn. Sorghum ( L. Moench) has been grown for centuries as a food crop in tropical areas where it has an increasing importance, particularly as a cereal option for people with celiac disease.
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- Microglia are immune cells in the brain that help maintain cellular health, but they might malfunction in Parkinson's disease (PD), particularly in relation to alpha-synuclein (αSyn) aggregation, which is a key feature of the disease.
- Research using human induced pluripotent stem cells showed that when microglia are exposed to both alpha-synuclein fibrils and inflammatory signals, it disrupts their ability to effectively manage and clear these aggregates.
- The study highlights that this model is useful for understanding microglial functioning in PD and reveals how inflammation affects their processing of alpha-synuclein, possibly worsening the disease state.
Objective: To investigate if a positive result on ReceptivaDx for evaluation of B-cell lymphoma 6 (BCL6), a proposed marker of progesterone resistance associated with impaired uterine receptivity, correlates with a suboptimal profile of receptivity-associated markers in the window of implantation using the endometrial receptivity array and single-nucleus transcriptomic analysis.
Design: Retrospective clinical cohort study; pilot study of single-nucleus RNA sequencing of prospectively collected window of implantation endometrium undergoing ReceptivaDx BCL6 evaluation.
Setting: Academic center.
Background: This study evaluates the procedural efficacy and patient experience of Contrast Enhanced Mammography (CEM)-guided biopsies performed in a prone position using the Giotto Class 30,000 system. The emphasis is on the procedural advantages and clinical outcomes for "enhancing-only lesions" (EOLs).
Methods: A retrospective analysis of 524 CEM examinations conducted from December 2023 to June 2024 at a tertiary referral center was performed.