An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFForebrain glial cells - ependymal cells and astrocytes -acquire upon injury- a "reactive" phenotype associated with parvalbumin (PV) upregulation. Since free radicals, e.g.
View Article and Find Full Text PDFThe article was originally published with one author missing. The name of the co-author Roman Moravcik was inadvertently omitted. His name and affiliation have now been added to the author list.
View Article and Find Full Text PDFVoltage-gated Ca channels are embedded in a network of protein interactions that are fundamental for channel function and modulation. Different strategies such as high-resolution quantitative MS analyses and yeast-two hybrid screens have been used to uncover these Ca channel nanodomains. We applied the yeast split-ubiquitin system with its specific advantages to search for interaction partners of the Ca2.
View Article and Find Full Text PDFCell Mol Life Sci
December 2018
The Ca-binding protein parvalbumin (PV) and mitochondria play important roles in Ca signaling, buffering and sequestration. Antagonistic regulation of PV and mitochondrial volume is observed in in vitro and in vivo model systems. Changes in mitochondrial morphology, mitochondrial volume and dynamics (fusion, fission, mitophagy) resulting from modulation of PV were investigated in MDCK epithelial cells with stable overexpression/downregulation of PV.
View Article and Find Full Text PDF