Impact of treatment for adolescent and young adults with essential thrombocythemia and polycythemia vera.

Essential thrombocythemia (ET) and polycythemia vera (PV) are rare in adolescent and young adult (AYA). These conditions, similar to those in older patients, are linked with thrombotic complications and the potential progression to secondary myelofibrosis (sMF). This retrospective study of ET and PV patients diagnosed before age 25 evaluated complication rates and impact of cytoreductive drugs on outcomes.

Validity of the DF-MOT to detect motor developmental delays in preterm children: A comparative study with the Bayley-III.

Background: The Motor Functional Development Scale for Young Children (DF-MOT) is a motor developmental scale originally designed and standardized for full-term children.

Aim: To validate the DF-MOT for diagnosing motor delays in preterm children, using the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III), as a reference.

Study Design: Prospective concurrent validity study.

Socio-spatial inequalities in presence of primary care physicians and patients' ability to register: A simulated-patient survey in the Paris Region.

Objectives: We studied the socio-spatial inequalities of three types of general practitioner (GP) density in the Paris metropolitan area: the density of GPs present (that is, practising) in the census block and of those registering new patients for office visits and, separately, for house calls.

Study Design: An exhaustive simulated patient survey enabled us to determine the number of GPs practising in the Paris metropolitan region accepting new patient registration for continuing care at their office and/or for house calls.

Methods: We measured at the level of a census block three types of GP densities: density of GPs present, density of GPs registering new patients at their office and density of GP registering new patients for house calls.