Publications by authors named "L Lane"
Article Synopsis
- The Human Proteome Project (HPP) aims to identify every protein-coding gene’s isoform and integrate proteomics into studies of human health and disease.
- Major updates include the retirement of neXtProt as the knowledge base, with UniProtKB now serving as the reference proteome, and GENCODE providing the target protein list.
- Recent data shows that 93% of protein-coding genes have been expressed, leaving 1,273 non-expressed proteins, along with the introduction of a new scoring system for functional annotation of proteins.
Article Synopsis
- - Oral Paxlovid is an effective treatment for COVID-19, preventing severe outcomes, but its use remains low among high-risk patients since its introduction in December 2021.
- - A July 2023 survey of 1,430 US adults revealed that 85% had little to no awareness of Paxlovid, with many holding incorrect beliefs about its effectiveness and side effects.
- - The lack of awareness and misunderstandings are particularly prevalent among disadvantaged groups, highlighting the need for improved public communication and outreach as the drug loses government subsidies.
Following burn injury, patients are at increased risk of infection and are often cited as having a high incidence of difficult-to-treat pathogens (DTp). The purpose of this study is to determine the incidence of DTp after burn injury, which factors are associated with their development, and subsequent outcomes. This single-center, retrospective study assessed patients with thermal or inhalation injury who had a positive culture resulting in initiation of treatment (i.
View Article and Find Full Text PDFThe enduring spread of COVID-19 and other respiratory viruses highlights a need for greater focus on long-term public willingness to perform protective behaviors. Although COVID-19 is no longer considered a public health emergency of international concern, it is unknown whether people in the United States plan to continue protective behaviors to protect themselves and others against infection. To inform planning and communications, we used a nationally representative survey of 1,936 US adults to examine attitudes and intentions toward future vaccination and mask-wearing.
View Article and Find Full Text PDFPurpose: State and local public health departments (LHDs) are encouraged to collaborate with community-based organizations (CBOs) to enhance communication and promote protective practices with communities made vulnerable during emergencies, but there is little evidence-based understanding of practical approaches to fostering collaboration in this context. This research focuses on how collaboration enhances LHD capacity for effective communication for people with limited English proficiency (LEP) during infectious disease outbreaks specifically and strategies to facilitate productive LHD-CBO collaboration.
Design: Qualitative, telephone interviews, conducted March-October 2021.