Publications by authors named "L Lampert"
Given the multidimensional aspect of pain, the assessment of treatment efficacy is challenging. The prospective observational multicenter PREDIBACK study aimed to assess, compare, and predict the effectiveness of different treatments for persistent spinal pain syndrome type 2 (PSPS-T2) using a digital tool and the Multidimensional Clinical Response Index (MCRI) including pain intensity, functional disability, quality of life, anxiety and depression, and pain surface. Results indicated that neurostimulation was the most effective treatment at 3-, 6-, 9-, and 12-month follow-up compared to baseline, leading to significant improvements in pain, function, and quality of life, whereas optimized medical management (OMM) and spinal reoperation showed no significant benefits.
View Article and Find Full Text PDFIntel's efforts to build a practical quantum computer are focused on developing a scalable spin-qubit platform leveraging industrial high-volume semiconductor manufacturing expertise and 300 mm fabrication infrastructure. Here, we provide an overview of the design, fabrication, and demonstration of a new customized quantum test chip, which contains 12-quantum-dot spin-qubit linear arrays, code named Tunnel Falls. These devices are fabricated using immersion and extreme ultraviolet lithography (EUV), along with other standard high-volume manufacturing (HVM) processes as well as production-level process control.
View Article and Find Full Text PDFBackground: Peripheral nerve stimulation (PNS) has emerged as a minimally invasive percutaneous procedure addressing neuropathic pain. However, the percutaneous cylindrical lead ultrasound-guided implantation procedure requires expertise that limits widespread PNS utilization. To overcome these challenges, a microinvasive endoscopy device has very recently been developed, enhancing the precision of PNS implantation by providing accurate visualization of the targeted nerve.
View Article and Find Full Text PDFArticle Synopsis
- Persistent spinal pain syndrome Type 2 (PSPS-T2) follows spinal surgery and has significant long-term effects, but research typically overlooks the ongoing nature of patient experiences.
- The PREDIBACK study tracked 200 patients over one year, identifying two patterns of health trajectories: 'persistent low health' (63.1%) and 'improving health' (36.9%).
- Factors like younger age, lower body mass index, and reduced pain intensity were linked to improved health outcomes, highlighting the potential of trajectory-based methods for better patient assessment and pain management.
Article Synopsis
- Spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRGS) are effective treatments for chronic pain after spinal surgery, and their combination (DUAL) may improve patient outcomes.
- A study compared the effectiveness of SCS, DRGS, and DUAL in providing at least 50% pain relief over a three-month period, finding that all methods had similar responder rates at this point but allowed for better results when options were switched.
- By the end of the 12-month follow-up, most patients showed significant clinical improvement, suggesting that personalized treatment through different stimulation options enhances pain management for chronic pain patients.