Publications by authors named "L Lahousse"
Background: Frailty is associated with increased susceptibility to medication-related harm, highlighting the importance of medication review for frail older adults. Community pharmacists are increasingly involved in the initiation of medication reviews. Yet, current frailty measurement methods are impractical in this setting.
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- Chronic obstructive pulmonary disease (COPD) can be influenced by genetic factors and may stem from reduced lung growth during childhood, leading to lower lung function throughout life.
- A polygenic risk score (PRS) was calculated using data from a large genome-wide association study and tested for its correlation with lung function in individuals aged 4-50 from multiple research cohorts.
- Results indicated that higher PRS scores were associated with significantly lower lung function, measured by key indicators, starting from childhood and continuing into adulthood, regardless of smoking, sex, or asthma diagnosis.
Article Synopsis
- * Data from 230,386 AF patients on OACs in Belgium revealed that those experiencing bleeding had a higher incidence of tumors, with 15.33 cases per 100 person-years compared to 5.22 cases for those without bleeding.
- * Specific types of bleeding, such as gastrointestinal and intracranial, significantly increased the risk of associated tumors, suggesting that bleeding could indicate hidden cancerous conditions.
Research suggests that respiratory and cardiovascular drugs can ameliorate the rate of lung function decline. To investigate the impact of respiratory and cardiovascular pharmacotherapy on lung function trajectories in the general population. Repeated spirometry was performed in the Rotterdam Study, a population-based cohort of adults aged ≥45 years.
View Article and Find Full Text PDFBackground: Assessing medication adherence is crucial in chronic obstructive pulmonary disease (COPD) management to prevent exacerbations. However, it is unclear whether this association between adherence and exacerbations is influenced by the adherence assessment methods or thresholds used. Electronic healthcare databases are valuable to study exacerbations and adherence in real life.
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