Publications by authors named "L Lagache"
Article Synopsis
- Researchers introduced "dry proteomics," a method that uses MALDI MSI to study the relationship between lipids and proteins in tissues, focusing on spatial localization.
- This approach was tested on rat brain tissue and later applied to human glioblastoma, revealing unique lipid signatures that correlate with specific proteins and biological pathways.
- Despite challenges with incomplete lipid data from glioblastoma patients, a classification model based on protein information was developed to enhance prognostic predictions and understand tumor heterogeneity.
Article Synopsis
- * A new multicentre study, called RECOVIDS, aims to explore how social vulnerability impacts recovery in patients who were hospitalized for ARDS related to COVID-19, incorporating both quantitative measurements and qualitative insights into patient experiences.
- * The study will examine patients admitted to intensive care for severe COVID-19 and track their lung health six months post-discharge, focusing on identifying lung sequelae through various tests and assessing the role of socio-economic status in their rehabilitation process.
The current gold-standard treatment for COVID-19-related hypoxemic respiratory failure is invasive mechanical ventilation. However, do not intubate orders (DNI), prevent the use of this treatment in some cases. The aim of this study was to evaluate if non-invasive ventilatory supports can provide a good therapeutic alternative to invasive ventilation in patients with severe COVID-19 infection and a DNI.
View Article and Find Full Text PDFCase Presentation: This clinical case presents the history of a woman hospitalized for acute respiratory distress syndrome (ARDS). A 62-year-old woman, with regular physical activity and no history of respiratory disease or smoking, was hospitalized for moderate ARDS with bilateral pneumonitis. Fourteen days later, she was discharged from the intensive care unit and received respiratory physical therapy.
View Article and Find Full Text PDFReproductive strategies of closely related species distributed along successional gradients should differ as a consequence of the trade-off between competition and colonization abilities. We compared male reproductive strategies of Quercus robur and Q. petraea, two partly interfertile European oak species with different successional status.
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