Publications by authors named "L Laberge"
Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.
Cochrane Database Syst Rev
November 2024
Article Synopsis
- Excessive daytime sleepiness is a frequent issue in myotonic dystrophy, prompting the use of psychostimulants to treat hypersomnia in these patients.
- The study aimed to evaluate the effectiveness of psychostimulants in alleviating hypersomnia symptoms in individuals with myotonic dystrophy, using data from randomized controlled trials.
- A total of six trials involving 136 adult participants were reviewed, suggesting a positive short-term impact of psychostimulants on improving wakefulness, with most trials showing low risk of bias.
Segmental Darier's disease is an uncommon subtype of Darier's genodermatosis, resulting from a mutation in the ATPase type 2 during early embryogenesis. It typically presents as a persistent, pruritic papular eruption following the lines of Blaschko. Histopathology of Darier's disease demonstrates acantholysis, dyskeratosis, and corps ronds.
View Article and Find Full Text PDFObjective: The aim of the study is to assess whether a blue-enriched light intervention improves nocturnal alertness and daytime sleep of night workers.
Methods: Thirteen miners performing 12-hour night shifts for 12 consecutive nights were exposed to a baseline and a blue-enriched light condition. All subjects wore an actigraph and completed a Psychomotor Vigilance Task at the beginning and at the end of each shift.
The objective was to characterize the progression of sleep complaints in 115 dystrophy type 1 (DM1) patients who filled out a sleep questionnaire twice at a 9-year interval. Daytime napping (22.1% vs.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers evaluated the impact of a 12-week strength training program on fatigue, daytime sleepiness, apathy, and overall disease burden in 11 men with DM1.
- * Results indicated that the training significantly reduced apathy and fatigue, with improvements noted even three to six months post-program, although there was no change in the overall disease burden.