Publications by authors named "L La Paglia"
Childhood obesity, sugar, and Early Childhood Caries: the sweet trap.
Eur J Paediatr Dent
December 2024
Article Synopsis
- - Sugar triggers the brain's dopamine system, leading to a preference for high-calorie foods and potentially contributing to "food addiction," which moves us away from healthier options over time.
- - Historically advantageous for survival, our craving for calorie-dense foods has now led to rising obesity and diabetes rates, posing significant public health concerns globally.
- - Recent studies indicate a notable increase in sugar consumption among youth, particularly through sugary drinks, correlating with a dramatic rise in obesity rates from 1990 to 2022.
Background: Current methods of monitoring cognition in older adults are insufficient to address the growing burden of Alzheimer disease and related dementias (AD/ADRD). New approaches that are sensitive, scalable, objective, and reflective of meaningful functional outcomes are direly needed. Mobility trajectories and geospatial life space patterns reflect many aspects of cognitive and functional integrity and may be useful proxies of age-related cognitive decline.
View Article and Find Full Text PDFBackground: This multicentric, retrospective study investigated the use of stereotactic body radiotherapy (SBRT) in patients (pts) with metastatic renal cell carcinoma (mRCC) who experienced oligoprogression during a combination therapy with an immune checkpoint inhibitor (ICI) and a tyrosine-kinase inhibitor (TKI).
Methods: We retrospectively evaluated 34 pts affected by oligoprogressive RCC treated with an ICI-TKI combination between January 2020 and December 2023. SBRT was delivered to each site of oligoprogressive metastatic disease.
Risk factors for Early Childhood Caries in Italian preschoolers: A cross-sectional analysis.
Eur J Paediatr Dent
December 2024
Aim: Early childhood caries (ECC) represent a relevant public health issue in paediatric population globally. The current study aimed to investigate the main risk factors of this condition.
Methods: This is a cross-sectional study carried out at the Child Dentistry Clinics of the Istituto Stomatologico Italiano, Milan, Italy, including patients aged 12-71 months and their parents.
Dentists, especially paediatric dentists, should inform their young patients of the treatment to be undertaken in an appropriate and comprehensive manner. In 1989, the UN Convention on the Rights of the Child (United Nations Convention on the Rights of the Child - UNCRC - https://www.unicef.
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