Development and Validation of KCPREDICT: A Deep Learning Model for Early Detection of Coronary Artery Lesions in Kawasaki Disease Patients.

Kawasaki disease (KD) is a febrile vasculitis disorder, with coronary artery lesions (CALs) being the most severe complication. Early detection of CALs is challenging due to limitations in echocardiographic equipment (UCG). This study aimed to develop and validate an artificial intelligence algorithm to distinguish CALs in KD patients and support diagnostic decision-making at admission.

Construction of a Vero cell line expression human KREMEN1 for the development of CVA6 vaccines.

Coxsackievirus A6 (CVA6) has emerged as a major pathogen causing hand, foot and mouth disease (HFMD) outbreaks worldwide. The CVA6 epidemic poses a new challenge in HFMD control since there is currently no vaccine available against CVA6 infections. The Vero cell line has been widely used in vaccine production, particularly in the preparation of viral vaccines, including poliovirus vaccines and EV71 vaccines.

Efficacy of concurrent balloon eustachian tuboplasty in the treatment of chronic otitis media with effusion in children with tonsil and adenoid hypertrophy.

Objective: This study aims to explore the clinical effects of simultaneous balloon eustachian tuboplasty (BET) in treating chronic secretory otitis media (COME) in children with bilateral tonsil and adenoid hypertrophy (TAH), providing a theoretical basis for the clinical application of BET.

Methods: From January 2023 to January 2024, 30 children diagnosed with COME and bilateral TAH were included in this retrospective study at our hospital. The cohort comprised a total of 55 affected ears.

Physical and emotional abuse with internet addiction and anxiety as a mediator and physical activity as a moderator.

This study aimed to explore the relationship between physical and emotional abuse (physical-emotional abuse) and Internet addiction in university students, as well as the mediating role of anxiety and the moderating role of physical activity. The data of physical-emotional abuse, anxiety and Internet addiction, and physical activity were measured by subjective questionnaire with convenience sampling in March 2024. A total of 1591 participants (806 males and 692 females) from Shanxi, Henan, Hunan and Hubei provinces in China were investigated.

Enhancing Catalytic Removal of Autoexhaust Soot Particles via the Modulation of Interfacial Oxygen Vacancies in Cu/CeO Catalysts.

The purification efficiency of autoexhaust carbon strongly depends on the heterogeneous interface structure between active metal and oxide, which can modulate the local electronic structure of defect sites to promote the activation of reactant molecules. Herein, the high-dispersion CuO clusters supported on the well-defined CeO nanorods were prepared using the complex deposition slow method. The formation of heteroatomic Cu-O-Ce interfacial structural units as active sites can capture electrons to achieve activation of the NO and O molecules.