Publications by authors named "L L Worth"
Objectives: We aimed to describe the characteristics of Clostridioides difficile infection (CDI) in cancer patients, analysing risk factors for 90-day recurrence and attributable mortality.
Methods: Retrospective analysis on all CDI episodes from 2020 to 2022 in three Australian hospitals and one Spanish hospital. Logistic regression analyses were performed.
Article Synopsis
- The study analyzed central line-associated bloodstream infections (CLABSI) in adult ICUs in Victoria, Australia, over 11 years, focusing on incidence rates, pathogens, and antimicrobial resistance.
- A total of 608 CLABSI events were reported, showing a significant decline in incidence from 1.39 to 0.70 per 1,000 central-line days, while the most common pathogen identified was coagulase-negative Staphylococci, with a 69.0% increase in infections caused by this organism.
- Despite the overall decrease in CLABSI, the study noted a stable trend in antimicrobial resistance rates, with a decrease in MRSA and increases in vancomycin and ceftriaxone-resistant pathogens,
Background: International consensus definitions for invasive aspergillosis (IA) in research are rigorous, yet clinically significant cases are often excluded from clinical studies for not meeting proven/probable IA case definitions. To better understand reasons for the failure to meet criteria for proven/probable infection, we herein review 47 such cases for their clinical and microbiological characteristics and outcomes.
Methods: Data on 47 cases that did not meet consensus IA definitions but were deemed significant were derived from a retrospective, observational, multicenter survey of 382 presumed IA cases across Australasia, of which findings of 221 proven/probable infections were recently published.
Article Synopsis
- The CONNECT-TBI study is examining how noninvasive neuromodulation can enhance cognitive training for military personnel with mild traumatic brain injury, specifically using the Attention Process Training-III (APT-III) program.
- A review of ten studies highlighted areas needing standardization in the APT-III administration to ensure reliable and uniform implementation across various sites and participants.
- Key areas requiring attention include dosage, adaptation of training, metacognitive strategy instruction, and goal attainment scaling, with the authors working towards creating a standardized process for these aspects.