Publications by authors named "L L Sobral"

Background: Cutaneous tuberculosis is a rare form of the disease that defies diagnosis due to the diversity of clinical presentations. This study was based on the reality of a dermatology referral center in the Brazilian Amazon region to detail several characteristics of this disease.

Objective: To describe a series of cases of cutaneous tuberculosis treated at a dermatology service in the Brazilian Amazon region, addressing epidemiological aspects, clinical forms, diagnostic methods, treatment, and outcomes.

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The study evaluated the effects of conventional pasteurization and ohmic heating (OH) at different electric fields (12, 16, 20, or 24 V/cm) on probiotic chocolate dairy desserts' physicochemical, microbiological, sensory properties and volatile profiles. Both treatments were analyzed for parameters such as pH, syneresis, cream stability index, rheology, bioactive compounds (total phenolics and antioxidant capacity), and probiotic viability (Lactobacillus acidophilus LA-05) over a 28-day storage period. Ohmic heating at higher electric fields (20 and 24 V/cm) showed comparable results to pasteurization for most parameters, with non-significant differences or even higher values for some.

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  • - Leprosy is a chronic infectious disease that affects peripheral nerves, leading to pain and decreased sensitivity, which can impair balance; measures such as center of pressure (COP) oscillations are important for evaluating balance in patients.
  • - The study aimed to validate the use of inertial sensors for assessing balance in leprosy patients by comparing the results to those obtained from a force platform.
  • - Results showed significant differences in balance parameters between leprosy patients and healthy controls, with the inertial sensors confirming the findings from the force platform, indicating their potential as a portable balance assessment tool.
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  • Gene expression helps cells adapt to stress, and a specific protein called P-TEFb plays a big role in how cells respond to heat and other stressors.
  • Researchers found that when pediatric brain cancer cells are treated with radiation, P-TEFb helps the cells quickly reorganize their DNA to repair damage and keep living.
  • Blocking P-TEFb while giving radiation treatment weakened the cells’ ability to adapt, making them more likely to die and improving survival time in experiments.
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Background: Oral Pathology (OP) and Oral Medicine (OM) are specialties in dentistry whose main objective is the diagnosis and treatment of oral and maxillofacial diseases, and aspects related to the academic training of professionals and fields of practice are distinct and heterogeneous around the world. This study aimed to evaluate professional training and areas of activity in OP and OM in Latin American countries.

Material And Methods: A questionnaire was sent to 11 countries, with a professional in each country responsible for answering it.

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