Publications by authors named "L L Shelton"
Background: This study aims to understand diagnosis communication experiences and preferences of youths with functional seizures and their parents.
Methods: Semistructured interviews with youths and their parents from a tertiary care children's hospital were conducted separately. We confirmed the diagnosis of functional seizures with the youth's treating providers.
Article Synopsis
- The study examines how oligoclonal bands (OCB) and the IgG index can help differentiate pediatric-onset multiple sclerosis (POMS) from other childhood diseases that can present similarly and may need urgent treatment.
- A retrospective review at a pediatric hospital revealed that among 85 cases, 36.5% were demyelinating diseases, with 14% confirmed as POMS, showing distinct laboratory findings compared to other conditions, including psychiatric issues and infections.
- The findings suggest that elevated IgG index and unique OCBs are more prevalent in demyelinating diseases, indicating that using an IgG index can quickly screen for these diseases in pediatric patients while waiting for OCB results
Article Synopsis
- - A patient in a minimally conscious state (MCS) showed significant improvement after being treated with Zolpidem, suggesting its potential benefits for similar patients
- - The study utilized medical records, patient care experiences, and literature reviews to support the findings on Zolpidem's effectiveness in MCS
- - The results highlight the need for more trials to explore Zolpidem as a treatment option in MCS while identifying factors that might predict which patients will benefit the most
Background: Whereas the National Comprehensive Cancer Network (NCCN) criteria restrict germline-genetic testing (GGT) to a subset of breast cancer (BC) patients, the American Society of Breast Surgeons recommends universal GGT. Although the yield of pathogenic germline variants (PGV) in unselected BC patients has been studied, the practicality and utility of incorporating universal GGT into routine cancer care in community and rural settings is understudied. This study reports real-world implementation of universal GGT for patients with breast cancer and genetics-informed, treatment decision-making in a rural, community practice with limited resources.
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