Publications by authors named "L L Sanders"
Cerebral venous sinus thrombosis is an uncommon sequela of low intracranial pressure, which may result from a lumbar puncture (LP). We describe a case of a patient in their 40s presenting with 48 hours of persistent headache following intrathecal administration of nusinersen for spinal muscular atrophy (SMA) type 3. There were no focal neurological signs or symptoms apart from baseline symmetrical proximal limb weakness attributed to SMA.
View Article and Find Full Text PDFIntroduction/aims: Electrophysiological investigations in early Guillain-Barré Syndrome (GBS) can be nondiagnostic. Improved testing for facial weakness in the early phase of GBS may improve diagnostic processes, as such weakness is found in approximately 50% of patients with GBS. This work pilots the utility of high-speed video analysis to complement blink reflex testing in early GBS.
View Article and Find Full Text PDFBackground: Results from observational studies suggest associations of red meat intake with increased risk of cardiovascular disease (CVD); however, RCTs have not clearly demonstrated a link between red meat consumption and CVD risk factors. Further, the specific effects of beef, the most consumed red meat in the United States, have not been extensively investigated.
Objectives: This study aimed to perform a systematic review and meta-analysis of RCT data evaluating the effects of minimally or unprocessed beef intake on CVD risk factors in adults.
Article Synopsis
- This systematic review focused on evaluating quality indicators for the primary prevention of cardiovascular disease (CVD) in primary care settings.
- Researchers analyzed 282 articles, ultimately reviewing 57, which resulted in the extraction of 726 quality indicators mainly categorized as process indicators.
- The study found that most indicators were related to assessing metabolic risk factors and lifestyle management, but only about 46% of the articles demonstrated strong methodological quality.
Article Synopsis
- Linking mothers to their newborns in health records helps assess the effects of policies and treatments on health over generations, but privacy issues limit access to traditional identifiers.
- A new scalable linking algorithm that uses Medicaid claims data without direct identifiers successfully connects mothers and infants while maintaining privacy.
- The algorithm linked 11.68 million mother-infant pairs across 50 states over 19 years, enabling important research on health determinants and the impact of public policy on families.