Publications by authors named "L L Porter"
Objective: Studies have found that cancer patients with dependent children exhibit high symptoms of anxiety, depression, and worry. Patients' parenting concerns can negatively impact their own and their family's adjustment to the cancer experience. However, relatively little is known about parenting concerns of partners of cancer patients, or associations between parenting concerns and couples' relationship adjustment.
View Article and Find Full Text PDFProteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction.
Curr Opin Struct Biol
January 2025
In recent years, advances in artificial intelligence (AI) have transformed structural biology, particularly protein structure prediction. Though AI-based methods, such as AlphaFold (AF), often predict single conformations of proteins with high accuracy and confidence, predictions of alternative folds are often inaccurate, low-confidence, or simply not predicted at all. Here, we review three blind spots that alternative conformations reveal about AF-based protein structure prediction.
View Article and Find Full Text PDFArticle Synopsis
- Sexual concerns are prevalent among breast cancer survivors, impacting their sexual adjustment significantly, which suggests that involving partners in the therapeutic process could be beneficial.
- The study tested the Intimacy Enhancement (IE) intervention, a telephone-based program for couples, to tackle these sexual issues, comparing its effectiveness to a control group intervention.
- Results indicated that the IE intervention led to notable short-term improvements in the sexual function and satisfaction of survivors, although sustaining these benefits over time may require additional strategies.
Background: Colorectal cancer (CRC) patients and their caregivers often experience multiple co-occurring symptoms (eg, fatigue, depression, anxiety, and sleep disturbance). There is a noticeable gap in research regarding symptom management for patient-caregiver dyads, particularly using technology-based tools.
Objective: This study aimed to describe the needs and perceptions of patient-caregiver dyads regarding a technology-based tool to manage their multiple symptoms.