Publications by authors named "L L Peluso"

Background: Approximately one-third of trauma-related deaths are due to traumatic brain injury (TBI), particularly among young adults and elderly patients. Management strategies may vary across different age groups, potentially influencing short-term neurological outcomes. This study aims to investigate age-related disparities in treatment approaches and 3-month neurological outcomes among TBI patients.

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: Elevated RDW has emerged in cardiac surgery as a potential means of preoperative risk stratification with the capacity to predict short- and long-term postoperative mortality, acute kidney injury, and postoperative atrial fibrillation. The question as to whether perioperative hemodynamic instability may be predicted by such a marker remains a topic of ongoing debate. The aim of this study was to explore the relationship between preoperative RDW and prolonged postoperative catecholamine use in minimally invasive mitral valve surgery.

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Background: Neurological complications have been observed in approximately 30% of hospitalized COVID-19 patients. The aim of this study was to evaluate whether early assessment of the Neurological Pupil Index (NPi) derived from an automated pupillometry could predict mortality in critically ill COVID-19 patients.

Methods: Retrospective cohort study of adult critically ill COVID-19 patients admitted to the intensive care unit of a University Hospital; patients without NPi measurement were excluded.

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Article Synopsis
  • Cerebral complications following cardiac arrest (CA) pose significant challenges globally, prompting research on sodium-ß-hydroxybutyrate (SBHB) as a potential treatment for brain injury in a swine model.
  • In an experiment with 20 adult swine, CA was induced, followed by 5 minutes of resuscitation, after which animals received either SBHB infusion or a control solution for 12 hours.
  • Results showed that SBHB infusion led to lower plasma biomarkers of brain injury and increased sEEG amplitude, indicating potential protective effects against cerebral damage after resuscitation.
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The seascape comprises multiple environmental variables that interact with species biology to determine patterns of spatial genetic variation. The environment imposes spatially variable selective forces together with homogenizing and diverging drivers that facilitate or restrict dispersal, which is a complex, time-dependent process. Understanding how the seascape influences spatial patterns of genetic variation remains elusive, particularly in coastal upwelling systems.

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