[Comparative efficacy of laboratory methods for cytomegalovirus detection in autopsy material].

Eighty eight autopsy specimens obtained from 30 fetuses, still-borns and infants died during the first year of life, all suspected for congenital virus infection at postmortem examination, were studied. The specimens were analyzed by 3 techniques: rapid culture method (RCM) for detection of cytomegalovirus (CMV) infectious activity, the immunocytochemical method for detection of CMV antigen in prints of organs and polymerase chain reaction (PCR) for detection CMV DNA. CMV was detected in 16 out of 26 specimens (61.

[Humoral antiviral immunity in children with hematologic neoplasms].

Antiviral humoral immunity was studied in patients with Hodgkin's disease, idiopathic thrombocytopenic purpura (ITP), and aplastic anemia (AA). Insufficiency of antiviral humoral immunity as regards antigenically unrelated viruses and Mycoplasma pneumoniae was characteristic of all these conditions. A remission of Hodgkin's disease and ITP was associated with a reliable increase of the studied parameters in comparison with the acute period of the disease.

[Characteristics of antiviral immunity in children with the atopic form of bronchial asthma].

In atopic bronchial asthma, an earlier "encounter" of children with viruses that cause acute respiratory diseases was established as was mass infection of asthma children with respiratory viruses. Disorders of antiviral immunity in children suffering from atopic asthma primarily manifested themselves in overproduction of antibodies among viruses. The leukocyte migration inhibition test has demonstrated that atopic asthma children are sensitized with respiratory viruses.