Psychosocial Factors are Associated With Walking-Related Goal Attainment in Multiple Sclerosis: A Preliminary Study.

Background: Many individuals with multiple sclerosis (MS) have difficulty walking, which may prompt a physical therapy (PT) referral. Psychosocial factors, including mood, pain, and social support, may affect patients' participation and overall success in meeting PT goals; however, this has yet to be examined in MS. This study aimed to explore the associations between walking-related PT goal attainment and psychosocial factors.

Direct oral anticoagulants versus vitamin K antagonists for cerebral venous thrombosis (DOAC-CVT): an international, prospective, observational cohort study.

Background: There is an unmet need for high-quality data from prospective studies on the safety and effectiveness of direct oral anticoagulants (DOACs) for the treatment of cerebral venous thrombosis (CVT). We aimed to compare the safety and effectiveness of DOACs versus vitamin K antagonists (VKAs) for the treatment of CVT in a setting that reflects daily clinical practice.

Methods: DOAC-CVT was an international, prospective, observational cohort study done in 65 hospitals in 23 countries across five continents.

Kidney stones in patients with Wilson's disease at a tertiary hospital in Northeastern Brazil.

Wilson's disease (WD) is an autosomal recessive disorder caused by mutations in the ATP7B gene leading to abnormal copper accumulation in tissues. Although the hepatic and neuropsychiatric effects of WD are well-documented, renal complications such as nephrolithiasis are less explored. This article examines the prevalence of nephrolithiasis and associated risk factors in a cohort of 36 WD patients.

Advancing Hydrogel-Based 3D Cell Culture Systems: Histological Image Analysis and AI-Driven Filament Characterization.

Machine learning is used to analyze images by training algorithms on data to recognize patterns and identify objects, with applications in various fields, such as medicine, security, and automation. Meanwhile, histological cross-sections, whether longitudinal or transverse, expose layers of tissues or tissue mimetics, which provide crucial information for microscopic analysis. : This study aimed to employ the Google platform "Teachable Machine" to apply artificial intelligence (AI) in the interpretation of histological cross-section images of hydrogel filaments.

Nutritional Status of Patients with Neoplasms Undergoing Ambulatory Chemotherapy and Associated Factors.

Background/objectives: Cancer, a leading cause of mortality globally and in Brazil, is influenced by environmental and behavioral factors, often linked to nutritional deficiencies such as low body mass index and muscle wasting, exacerbating prognostic outcomes and mortality rates. Timely nutritional interventions during chemotherapy are pivotal, necessitating continuous nutritional assessment for effective patient care management. This study aimed to assess the nutritional status of non-metastatic cancer patients undergoing chemotherapy and identify factors influencing their nutritional status.