Publications by authors named "L L Lunardi"
Background: Patient activation refers to the knowledge, confidence and skills required for the management of chronic disease and is antecedent to self-management. Greater self-management in chronic kidney disease (CKD) results in improved patient experience and patient outcomes.
Aim: To examine patient activation levels in people with CKD stage 5 pre-dialysis and determine associations with sociodemographic characteristics, treatment adherence and healthcare utilisation.
Human ribonuclease (RNase) 1 and bovine RNase A are the proto-types of the secretory "pancreatic-type" (pt)-RNase super-family. RNase A can oligomerize through the 3D domain swapping (DS) mechanism upon acetic acid (HAc) lyophilisation, producing enzymatically active oligomeric conformers by swapping both N- and C-termini. Also some RNase 1 mutants were found to self-associate through 3D-DS, however forming only N-swapped dimers.
View Article and Find Full Text PDFArticle Synopsis
- Chronic kidney disease (CKD) affects a person's health long-term, and people with CKD need to manage their condition effectively, which is known as patient activation.
- The study aimed to assess how effective interventions for increasing patient activation are in improving health-related behavior outcomes for individuals with CKD stages 3-5.
- The meta-analysis found that certain interventions significantly improved self-management and self-efficacy among participants, but had limited impact on quality of life and medication adherence, suggesting that personalized education and problem-solving strategies may enhance self-management efforts.
The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count, even without antiretrovirals. There is a lot of diversity in HIV subtypes and HLA alleles.
View Article and Find Full Text PDFObjective: This review aims to examine the effect of patient activation interventions compared with usual care on health-related behavioral outcomes in adults with chronic kidney disease stages 3-5.
Introduction: Chronic kidney disease is a global health problem associated with a high mortality, reduction of health-related quality of life, and high health care costs. The chronic nature requires active involvement and self-management of the person with chronic kidney disease.