Publications by authors named "L L Lerner"
Patients with chronic inflammation are burdened with anemia of inflammation (AI), where inflammatory cytokines inhibit erythropoiesis, impede erythropoietin production, and limit iron availability by inducing the iron regulator hepcidin. High hepcidin hinders iron absorption and recycling, thereby worsening the impaired erythropoiesis by restricting iron availability. AI management is important as anemia impacts quality of life and potentially affects morbidity and mortality.
View Article and Find Full Text PDFTo compare post-operative bleeding measures in patients who underwent prostatic artery embolization (PAE) prior to water-jet ablation (aquablation) vs. water-jet ablation alone. A retrospective review identified 145 patients treated with water-jet ablation for benign prostatic hyperplasia from December 2018 to June 2021.
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- Systemic Epstein-Barr virus-positive T-cell lymphoma (TCL) in children is rare and often follows an EBV infection, leading to a hyperinflammatory state and poor outcomes, often presenting with hemophagocytic lymphohistiocytosis (HLH) syndrome.
- The disorder involves a hyperactive immune response and may be linked to genetic alterations on chromosome 22q11.2, increasing the risk of non-Hodgkin lymphoma later in life.
- A case study of a 21-year-old male who developed HLH from an EBV infection ultimately resulted in a diagnosis of systemic EBV TCL, and despite treatment, he did not survive before receiving a stem cell transplant, highlighting the need for awareness
Introduction: Benign prostatic obstruction (BPO) is one of the most common causes of male lower urinary tract symptoms. Some institutions routinely perform BPO surgeries in ambulatory setting, while others elect for overnight hospitalization. With the COVID-19 pandemic limiting resources and hospital space for elective surgery, we investigated the time trend of ambulatory BPO procedures performed around the COVID-19 outbreak.
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- The study examined the association between SGLT2 inhibitors and the risk of urinary tract infections (UTIs) in men, focusing on older men at higher risk for voiding issues.
- Using a global drug safety database (VigiBase), researchers analyzed data from 1967 to 2022, finding significantly elevated risks for both UTIs and complex UTIs among men, especially those aged 65 and older.
- The findings indicate that while SGLT2 inhibitors are beneficial for diabetes, healthcare providers need to be cautious due to the increased risk of UTIs, particularly in older men who may have existing urinary health issues.