Publications by authors named "L L Lazaro"
This study evaluates the impact of various processing steps in the human milk (HM) donation chain on nutritional composition and oxidative biomarkers, specifically focusing on triacylglycerols, glucose, polyphenols, and lipid peroxides. A total of 68 HM samples were collected from the Human Milk Bank of Córdoba (Argentina) between 2022 and 2023. The effects of storage and pasteurization using the Holder method were assessed.
View Article and Find Full Text PDFSome autoimmune diseases, including rheumatoid arthritis (RA), are preceded by a critical subclinical phase of disease activity. Proactive clinical management is hampered by a lack of biological understanding of this subclinical 'at-risk' state and the changes underlying disease development. In a cross-sectional and longitudinal multi-omics study of peripheral immunity in the autoantibody-positive at-risk for RA period, we identified systemic inflammation, proinflammatory-skewed B cells, expanded Tfh17-like cells, epigenetic bias in naive T cells, TNF+IL1B+ monocytes resembling a synovial macrophage population, and CD4 T cell transcriptional features resembling those suppressed by abatacept (CTLA4-Ig) in RA patients.
View Article and Find Full Text PDFPurpose: Few studies have assessed trochanteric vascularity despite its implications for bone healing and surgical approaches. This study aimed to assess the regional arterial contributions of the medial femoral circumflex artery (MFCA) versus the lateral femoral circumflex artery (LFCA) to trochanteric vascularity.
Methods: Ten adult human cadaveric pelvises to mid-femur specimens were obtained.
Article Synopsis
- Wastewater-based surveillance is an effective method for tracking virus spread in communities, especially where traditional monitoring is lacking, as seen in São Tomé and Príncipe.
- A study analyzed 122 water samples over 13 months, identifying high levels of human contamination and varying prevalence rates of multiple viral pathogens, including Hepatitis A and SARS-CoV-2.
- Results indicate significant continuous circulation of SARS-CoV-2, even when no cases were reported, highlighting the potential of wastewater monitoring in understanding community virus transmission.