Publications by authors named "L L Kelsey"
Introduction: The complex arborization of the feto-placental vasculature is crucial for optimal fetal nutrition, waste exchange and ultimately, development. Ethical and experimental limitations constrain research into the human placenta, hence experimental animal models such as mice and rats, are crucial to understand placental function. It is unclear how well the mouse and rat feto-placental vascular structure emulates human.
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- - Researchers are investigating the causes of spaceflight-associated neuro-ocular syndrome (SANS) and found that simulated microgravity (tail suspension in mice) might affect retinal blood vessels, potentially causing dysfunction.
- - Using advanced imaging and computational techniques, the study examined the eye samples, revealing that tail-suspended mice had shorter and fewer small blood vessels with increased wall shear stress and pressure compared to control mice.
- - The results suggest a potential connection between space-like environments and changes in retinal health, which could be relevant for understanding SANS, highlighting the need for further research with larger sample sizes.
Background & Purpose: (1) Evaluate efficacy of an abbreviated total spine protocol in triaging emergency department (ED) patients through retrospective evaluation. (2) Describe patient outcomes following implementation of a rapid cord compression protocol.
Methods: (1) All contrast-enhanced total spine magnetic resonance imaging studies (MRIs) performed on ED patients ( = 75) between 10/1-12/31/2022 for evaluation of cord compression were included.
As the International Space Station comes to the end of a transformative era of in-space research, NASA's Commercial Low Earth Orbit (LEO) Destinations (CLD) Program aims to catalyze a new generation of platforms with co-investment from the private sector, preventing a potential gap in research performed in LEO, while building a robust LEO economy. In this paper, we provide insight into the CLD Program focusing on Orbital Reef, describing its operational and technical characteristics as well as new opportunities it may enable. Achieving about a third of the pressurized volume of the ISS with the launch of a single pressurized module and growing to support hundreds of Middeck Locker Equivalents (MLE) in passive and active payloads internally and externally, Orbital Reef will enable government, academic, and commercial institutions to continue and expand upon research and development (R&D) efforts currently performed on ISS.
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