Immunological and central nervous system changes in mice suffering from Staphyloccocus aureus and treated with Saccharomyces cerevisiae var. vini living cells.

The influence of Saccharomyces cerevisiae var. vini viable cells on the Staphylococcus aureus-suffering mice was ascertained: (1) effect of S. aureus living cells on antibacterial and antitoxic antibodies, (2) effect of S.

[Use of polypeptide growth factors for the acceleration of vascular prosthesis healing].

The authors describe results of experimental investigations proving the possibility to use polypeptide growth factors from the brain of animals for the stimulation of neogenesis of the vascular wall cells. The method was used for plasty of the vessels with biological and artificial prostheses. Patency of the prostheses in experiment was noted in observations during 180 days.

[DNA structure in the particles of 5 bacteriophages from the data of circular dichroism].

DNA optical activities in situ were studied in the particles of five medium sized bacteriophages (SB1, F15; IRA, SD and T7). Delta epsilon in the CD spectrum of intraphage DNA is not shown to correlate with the sizes of phage heads or with the light scattering characteristics of phage suspension. Bacteriophage SB1, studied for the first time, has the amplitude of CD spectrum in the 260-300 nm region higher, than the CD spectrum of its free phage DNA.

[Two types of structural organization of double-stranded DNA in phage particles].

Structural arrangement of linear unmodified duplex DNA in phage particles FI5 and SB1 was studied by the techniques of absorption spectrum, CD, scanning microcalorimetry. Hyperchromism is not registered for SB1 DNA in situ at 260 nm, in contrast to FI5 and other phages, but is visible at 260-290 nm. Phage SB1 had an unusual CD spectrum: intensity of the positive band at 280 nm was, practically, identical to the free SB1 DNA intensity.

[New type of DNA structural organization in the composition of bacteriophage Sb-1 particles].

Spectrophotometric melting and chemical modification procedures were used for comparative study of parameters of DNA structure in particles of phages Sb-1 and FI-5 possessing spherical symmetry of the heads. Like in other phages of this morphological group, some part of DNA structure in FI-5 phage particles is disarrayed and has changed reactive capacity of basic aminogroups. Another type of DNA structural organization in situ was found with staphylococcal phage Sb-1.