Single-pulse transcranial magnetic stimulation of the dorsolateral prefrontal cortex does not directly affect muscle sympathetic nerve activity in humans.

Transcranial magnetic stimulation (TMS) is applied both in research settings and clinically, notably in treating depression through the dorsolateral prefrontal cortex (dlPFC). We have recently shown that transcranial alternating current stimulation of the dlPFC partially entrains muscle sympathetic nerve activity (MSNA) to the stimulus. We, therefore, aimed to further explore the sympathetic properties of the dlPFC, hypothesizing that single-pulse TMS could generate de novo MSNA bursts.

Emotional inertia is independently associated with cognitive emotion regulation strategies and sleep quality.

Emotional inertia (i.e. the tendency for emotions to persist over time) is robustly associated with lower wellbeing.

Integrated, Scaffolded, and Mandatory Community and Shelter Medicine Curriculum: Best Practices for Transformational Learning on Access to Veterinary Care.

Within veterinary medical education, there is increasing focus on equity and cultural competency/humility, especially within service learning in community and shelter medicine. This article reviews the current literature and draws from the experience of the Ontario Veterinary College Community Healthcare Partnership Program's development of a community and shelter medicine curriculum. We propose that to graduate veterinarians with the knowledge and skills to address inequities in access to veterinary care, a best practice is to integrate mandatory in-class and experiential learning activities, scaffolded across the curriculum.

Utilizing composite recyclate as reinforcement in inverse-vulcanised polymers.

A sustainable approach to prevent filler settling in vitrimeric polymers, using a mechanically recycled composite filler, is reported. The resulting composites demonstrate over 40% improvements in flexural strength and an over 70% improvement in material hardness while maintaining recyclability and mechanical performance after remanufacturing.

The 'T paradox' in inflammatory arthritis.

Classic regulatory T (T) cells expressing CD4 and the hallmark transcription factor FOXP3 are integral to the prevention of multi-system autoimmunity. However, immune-mediated arthritis is often associated with increased numbers of T cells in the inflamed joints. To understand these seemingly conflicting observations, which we collectively describe as 'the T paradox', we provide an overview of T cell biology with a focus on T cell heterogeneity, function and dysfunction in arthritis.