[Comparative evaluation of selenium enriched bakerrs yeast autolysate and its soluble fraction antigenic properties].

Circulating IgG antibodies were measured in 192 sera of children aged from 4 months to 17 years suffering from different forms of food hypersensitivity against antigen of selenium enriched baker's yeast autolysate and its soluble fraction and also against antigens of 24 common foods (milk, egg, meat, vegetables, fruits). It was shown that yeast autolysate could be attributed as a product with weak sensitizing activity if antibody titers were compared in general group of patients or in children aged below 3 years. Removal of cell's coats from centrifugation clarified autolysate diminished its sensitizing properties in great extent.

[Effect of biologically active food additives containing autolysate of baker's yeast and spirulina on intestinal permeability in an experiment].

Influence of bioactive food supplements (BFA) intake on intestinal barrier permeability to macromolecules of polyethylene glycol 4000 was studied in rats with intestinal anaphylaxis and after external gamma-irradiation. BFA studied included autolysed baker's yeast ("Vitasil") and edible algae Spirulina platensis. Intake of complex additive Vitasil + Spirulina resulted in significant diminution of permeability before irradiation and its partial normalization (24% decrease) after irradiation.

[Effect of a bioactive food supplement from selenium enriched baker's yeast autolysate on the status of the intestinal barrier in rats with anaphylaxis].

Rat's intestinal barrier permeability disturbed in consequence of intestinal anaphylaxis reaction was almost completely normalized in animals fed with baker's yeast autolysate "Vitasil" enriched with selenium on a level of 3 mg Se/day during 29 days. These rats showed in comparison to Se-unsupplemented animals a significant elevation of Se level in red blood cells and plasma together with a decrease of intestinal mucosal TCA-soluble thiol compounds. Urinary Se excretion was significantly elevated in comparison to unsensitized rats both in Se-supplemented and unsupplemented animals with anaphylaxis.