Publications by authors named "L L Chappell"
Background/objectives: Rodents provide a useful translational model of fear- and anxiety-related behaviors. Previously stressed animals exhibit physiological and behavioral stress responses that parallel those observed in anxious humans. Patients diagnosed with post-traumatic stress disorder (PTSD) present with a spectrum of debilitating anxiety symptoms that result from exposure to one or more traumatic events, with individuals exposed to early adverse experiences and women having increased vulnerability for diagnoses; however, the mechanisms of this increased vulnerability remain unknown.
View Article and Find Full Text PDFParsnips () are a speciality UK crop with an economic value of at least 31M GBP annually. Currently, the major constraints to production are losses associated with root canker disease due to a range of fungal pathogens, among which is of most concern to growers. With limited research conducted on this species, this work aimed to provide a much-needed characterisation of isolates from across the UK, continental Europe, and New Zealand.
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- The COVID-19 pandemic increased the reliance on telemedicine, particularly in maternity care, leading to the BUMP trials which evaluated self-monitoring blood pressure for pregnant individuals at risk of hypertension.
- Qualitative interviews with 39 pregnant women revealed that while self-monitoring was generally seen as reassuring and empowering, it also created uncertainty and added responsibility, causing some women to opt out of the intervention.
- Ultimately, the BUMP trials did not demonstrate significant improvements in early detection or management of hypertension from blood pressure self-monitoring in pregnant women at higher risk for preeclampsia.
Article Synopsis
- Actively involving pregnant individuals in self-monitoring their health, such as blood pressure and protein levels, is becoming a common practice, especially for those with hypertension.
- Research on self-monitoring blood pressure shows acceptance, but there's limited evidence on self-testing for proteinuria and its impact on traditional maternity care structures.
- A qualitative study involving interviews and focus groups revealed a positive view of participatory monitoring among both pregnant people and professionals, but highlighted concerns about maintaining professional oversight and how healthcare access might be influenced by judgments on who is fit to self-test.