Publications by authors named "L L Brinkley"
Cholera is a diarrhoeal disease caused by . It remains a major public health challenge in the endemic region around the Bay of Bengal. Over decadal time scales, one lineage typically dominates the others and spreads in global pandemic waves.
View Article and Find Full Text PDFArticle Synopsis
- Horseshoes significantly affect the safety and performance of racehorses by providing necessary traction while managing hoof slip, which can help reduce stress and potential injuries.
- The study measured hoof slip duration in retired Thoroughbreds galloping on turf and artificial tracks with different shoeing setups using high-speed video, analyzing data from 389 hoof interactions.
- Findings revealed that slip duration varied among shoeing conditions and surfaces, with the leading hindlimb typically having the shortest slip duration, while turf generally resulted in longer slip durations for most limbs compared to artificial track surfaces.
Article Synopsis
- A study examined factors connected to long-term neurodevelopmental delays in children who underwent heart transplants, using data from over 3,800 pediatric patients.
- Results showed that those with definitive motor or cognitive delays had higher rates of congenital heart disease, needed ventilator support during transplant, and had a history of stroke before discharge.
- Patients with neurodevelopmental delays also experienced worse survival outcomes, with significant correlations found between pre-existing stroke conditions and the likelihood of developing these delays post-transplant.
Hypercyanotic spells are one of the defining clinical features of Tetralogy of Fallot (TOF). Limited data exist on peak Doppler right ventricular outflow tract (RVOT) gradient as a risk factor for the development of hypercyanotic spells, frequency of prophylactic use of propranolol based on peak RVOT gradient, and its impact on preventing the occurrence of hypercyanotic spells. We aimed to quantify peak RVOT gradients as measured on transthoracic echocardiography in infants with unrepaired TOF and assess for correlation with clinical symptoms of hypercyanotic spells.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how bacteriophages interact with cholera bacteria in diarrheal disease patients in Bangladesh over a year-long period.
- It finds that virulent phages and antibiotics can suppress cholera bacteria differently, depending on the bacteria's resistance mechanisms, which affects the severity of dehydration in patients.
- The research emphasizes the importance of understanding phage-bacteria coevolution for developing effective phage-based treatments and diagnostics.