Performance characteristics and relationship of PSA value/kinetics on carbon-11 acetate PET/CT imaging in biochemical relapse of prostate cancer.

An elevated serum prostate-specific antigen (PSA) level alone cannot distinguish between local-regional recurrences and distant metastases after treatment with curative intent. With available salvage treatments, it has become important to localize the site of recurrence. C-Acetate PET/CT was performed in patients with rising PSA, with statistical analysis of detection rates, sites/location of detection, PSA kinetics and comparison with other tracers (FDG and Choline).

Impact of NADiA ProsVue PSA slope on secondary treatment decisions after radical prostatectomy.

Background: Selecting appropriate candidates for postprostatectomy radiotherapy is challenging, because adverse pathological features cannot accurately predict clinical recurrence. Biomarkers that identify residual disease activity may assist clinicians when counseling patients on the risks, benefits and costs of secondary treatment. NADiA ProsVue PSA slope results ≤2.

Transitional cell carcinoma of the fossa navicularis of the male urethra.

We report a case of transitional cell carcinoma arising in the fossa navicularis, a portion of the male urethra ordinarily lined by squamous epithelium. This is the third reported case of transitional cell carcinoma of the distal urethra. The neoplasm metastasized to superficial inguinal lymph nodes.