Publications by authors named "L Kroger"
The serine/threonine kinase CK2 (formerly known as casein kinase II) plays a crucial role in various CNS disorders and is highly expressed in various types of cancer. Therefore, inhibiting this key kinase could be promising for the treatment of these diseases. The CK2 holoenzyme is formed by the recruitment of two catalytically active CK2α and/or CK2α' subunits by a regulatory CK2β dimer.
View Article and Find Full Text PDF[Postgraduate Training: eLogbook, Entrustable Professional Activities & Co.].
Anasthesiol Intensivmed Notfallmed Schmerzther
October 2024
Article Synopsis
- The shift from traditional time-based medical training to competency-based medical education (CBME) focuses on the actual skills and competencies that physicians need, as outlined by frameworks like CANMEDs.
- Germany has made competency-based training mandatory, but critics argue that CBME can be too theoretical and not closely linked to real-world clinical practice.
- To bridge this gap, Entrustable Professional Activities (EPA) have been introduced, describing specific clinical tasks trainees can be trusted to perform, emphasizing the importance of collaboration and feedback among all stakeholders for successful implementation of CBME.
Incident reporting and learning systems provide an opportunity to identify systemic vulnerabilities that contribute to incidents and potentially degrade quality. The narrative of an incident is intended to provide a clear, easy to understand description of an incident. Unclear, incomplete or poorly organized narratives compromise the ability to learn from them.
View Article and Find Full Text PDFArticle Synopsis
- - Granuloma faciale is a rare, benign skin condition that causes solitary or multiple lesions on the face, known for its pattern of flare-ups without spontaneous resolution.
- - Treatment options for granuloma faciale, including topical, systemic, surgical, and laser therapies, have limited success, and the condition often recurs after treatment.
- - A case study describes a male patient with persistent granuloma faciale who achieved a successful outcome with a combination of surgery and pulsed-dye laser therapy, maintaining remission for nearly a year.