Publications by authors named "L Kretschmer"
Article Synopsis
- The study investigates early cellular responses to SARS-CoV-2 infection using single-cell profiling in individuals with no prior immunity to the virus.
- Significant changes in cell types and immune responses were observed over time, indicating different patterns of infection severity, especially in nasopharyngeal regions.
- Key findings suggest that early interferon responses and specific immune cell behaviors, like high expression of HLA-DQA2, could be crucial in preventing sustained infections, while a novel computational tool, Cell2TCR, enhanced the analysis of T cell responses.
Gender differences in the distribution of children's physical activity: evidence from nine countries.
Int J Behav Nutr Phys Act
September 2023
Article Synopsis
- Research shows that physical activity patterns in childhood may affect long-term health, with previous studies indicating that boys are generally more active than girls, mainly focusing on average activity levels rather than full distribution across intensities.
- A study using data from 15,461 children across 9 countries analyzed gender differences in physical activity using accelerometry, focusing on various intensities: Sedentary, Light, and Moderate-to-Vigorous (MVPA).
- Results revealed boys had higher average levels of MVPA and counts per minute, with greater variability in their activity, while girls had a more uniform distribution; this highlights the need for targeted interventions addressing gender disparities in MVPA.