Publications by authors named "L Koschinski"
Article Synopsis
- Planar microelectrode arrays (MEAs) struggle with low spatial resolution and signal-to-noise ratio, limiting their effectiveness in understanding neuronal functions.
- A novel 3D printing method combined with thin film technology creates customizable MEAs that are physically robust and capable of recording neural activity across different applications.
- These advanced 3D MEAs facilitate research in both normal and pathological conditions, enhancing capabilities for drug screening and neuromodulation studies.
The combination of electrophysiology and neuroimaging methods allows the simultaneous measurement of electrical activity signals with calcium dynamics from single neurons to neuronal networks across distinct brain regions . While traditional electrophysiological techniques are limited by photo-induced artefacts and optical occlusion for neuroimaging, different types of transparent neural implants have been proposed to resolve these issues. However, reproducing proposed solutions is often challenging and it remains unclear which approach offers the best properties for long-term chronic multimodal recordings.
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