Publications by authors named "L Khin"
Background & Aims: This study assessed the association of remission of type 2 diabetes mellitus (DM) or metabolic dysfunction-associated steatotic liver disease (MASLD)/related SLD (r-SLD; MASLD with excessive alcohol intake) as defined by the fatty liver index with the risk of cardiovascular disease (CVD).
Methods: Health examination data at baseline and after 2 years (2-Years) were extracted from a nationwide claims database in Japan. Among participants aged 18-72 years with at least 3 years of follow-up, 9345 participants with DM-associated MASLD/r-SLD and 71 932 participants with non-DM MASLD/r-SLD at baseline were included in the study.
Introduction: Traditional risk factors do not fully explain the increased risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA). The 2-2 genotype confers a lower anti-oxidant and higher inflammatory effect on the vasculature compared to the non- 2-2 genotype. This study investigates the association of the genotype with CVD in patients with RA.
View Article and Find Full Text PDFBackground: We evaluated the feasibility, safety, and efficacy of a 2D-planar robot for minimally supervised home-based upper-limb therapy for post-stroke hemiparesis.
Methods: The H-Man, end effector robot, combined with web-based software application for remote tele-monitoring were evaluated at homes of participants. Inclusion criteria were: strokes > 28 days, Fugl-Meyer Motor Assessment (FMA) > 10-60/66, presence of a carer and absence of medical contraindications.
Article Synopsis
- The study aimed to investigate how low-density lipoprotein cholesterol (LDL-C) levels are linked to the occurrence of coronary artery disease (CAD), especially when factoring in high-density lipoprotein cholesterol (HDL-C) levels and glucose status.
- It analyzed data from over 1.5 million individuals without previous CAD for the years 2008-2019, using Cox proportional hazards modeling to assess the risk of CAD based on different cholesterol and glucose levels.
- The findings revealed that lower LDL-C levels combined with low HDL-C levels increased the risk of developing CAD significantly, emphasizing the need for personalized treatment strategies targeting LDL-C according to a patient's HDL-C levels and glucose tolerance.
Aims: To determine the association between the magnitude of weight loss and incidence of remission according to baseline characteristics in patients with diabetes in clinical settings.
Methods: In total, 39 676 Japanese patients with type 2 diabetes aged ≥18 years with glycated haemoglobin (HbA1c) ≥6.5% and/or glucose-lowering drug prescription were identified from databases of specialists' clinics from 1989 and followed until September 2022.