Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis.

Purpose: To evaluate the efficacy of the novel oXiris® membrane in critically ill adult patients.

Methods: We systematically searched MEDLINE, EMBASE, and CENTRAL from inception to 01/06/2023 for relevant randomised controlled trials (RCTs) and non-randomised studies of intervention (NRSI). The primary outcome was overall mortality.

Polyethylene glycol hypersensitivity, patient outcomes in a 7-year retrospective study.

Background: Immediate IgE-mediated hypersensitivity reactions to polyethylene glycol (PEG) are rare. Our understanding of PEG hypersensitivity is limited.

Objective: To evaluate the clinical characteristics and investigation outcomes of the largest cohort of patients with PEG allergy reported.

Vitamin B Hypersensitivity: A Retrospective Multicenter Study.

Background: Vitamin B (Vit B) deficiency affects approximately 20% of those above the age of 60 years in the United Kingdom and United States. If untreated, it leads to detrimental health outcomes.

Objective: To investigate a cohort of patients with Vit B hypersensitivity (VB12H) referred to 3 UK allergy centers and design a pathway for the investigation of VB12H.