Publications by authors named "L Kh Pen"
Coexistence of Fabry Disease and Membranous Nephropathy: A Case Report.
Iran J Kidney Dis
August 2024
Article Synopsis
- * A renal biopsy revealed abnormal deposits in the glomeruli and features indicating FD, supported by a specific genetic mutation and low enzyme activity confirming the diagnosis.
- * After treatment with ramipril initially reduced protein levels in urine, the proteinuria returned, leading to ongoing treatment with allisartan isoproxil, which has not yet been effective in resolving the issue.
Article Synopsis
- The study aimed to translate and assess the Autism Spectrum Knowledge Scale General Population Version (ASKSG) for parents, focusing on its reliability and validity in understanding autism spectrum disorder (ASD).
- A cross-sectional analysis involving 858 parents in China was performed, utilizing demographic forms and the ASKSG to evaluate knowledge about ASD, with multiple psychometric assessments conducted.
- Results indicated a strong reliability for ASKSG (Cronbach's alpha of 0.865), identified five key factors from exploratory factor analysis, and highlighted some differences in item performance between genders, suggesting variation in how ASD knowledge is understood.
Article Synopsis
- The study aimed to create a method to select HLA compatible platelets for patients experiencing immune platelet transfusion failure (IPTR) by combining two techniques: mean fluorescence intensity (MFI) grading and the HLAMatchmaker program for identifying donor-patient epitope mismatches.
- Researchers conducted a comprehensive analysis involving 7,807 platelet (PLT) cross-matching tests and categorized MFI results into different positivity groups, allowing for a thorough evaluation of HLA Class I antibody levels in the patients.
- Results showed significant differences in the positive reactions from the cross-matching tests, suggesting that the combined approach of avoiding high MFI threshold antigens and minimizing epitope mismatches effectively improves the
Purpose: To investigate the value of intratumoral and peritumoral radiomics based on contrast-enhanced computer tomography (CECT) to preoperatively predict microsatellite instability (MSI) status in gastric cancer (GC) patients.
Methods: A total of 189 GC patients, including 63 patients with MSI-high (MSI-H) and 126 patients with MSI-low/stable (MSI-L/S), were randomly divided into the training cohort and validation cohort. Intratumoral and 5-mm peritumoral regions' radiomics features were extracted from CECT images.
HLA-C*08:99 differs by one non-synonymous nucleotide from C*08:01:01 in exon 5, codon 288 GTT>ATT.
View Article and Find Full Text PDF